Amidopyrine, Paracetamol and Caffeine Tablets for The Improvement of Neuralgia, Active Rheumatic Pain and Dysmenorrhea

• Customization: Available
• Transport Package: Carton
• Specification: 20x15x15cm
• Model NO.: CF020-1
• Origin: China
• Production Capacity: 100000/Month

Product Description

[Drug name] General name: Amaminophenka Capsules

Market name: Heat

English name: Anlin Fen Ka Jiaonang

Pinyin: Anlin Fen Ka Jiaonang

Ingredients This product is a compound preparation, its components are: Aminopyrine 0.15g, acetaminophen 0.127g, caffeine 50mg per tablet.

Properties This product is a hard capsule, the contents of white powder.

[Indications] For the improvement of fever, headache, arthralgia, neuralgia, active rheumatic pain and dysmenorrhea and other symptoms.

[Usage and Dosage] Oral administration. One capsule at a time, 1-3 times a day.

[Adverse Reactions] 1. Aminopyrine contained in this compound has obvious adverse reactions. Taking Aminopyrine can cause vomiting, rash, fever, excessive sweating and stomatitis, etc., and a few may cause neutrophilia, aplastic anemia, exudative erythema, exhumative dermatitis, glans erosion, etc. 2. At conventional doses of acetaminophen, there are few adverse reactions, and in a few cases, granulocytosis, anemia, atopic dermatitis (rash, pruritus, etc.), hepatitis, or thrombocytopenia may occur. 3. Long-term heavy use of acetaminophen, especially in people with low renal function, can lead to renal colic or acute renal failure (oliguria, uremia), or chronic renal failure (analgesic drug nephropathy). 4. Caffeine is habitually taken too much for a long time, which can lead to headache, tension, excitement and anxiety.

1. Gastrointestinal bleeding is contraindicated. 2. It is forbidden for people with digestive tract ulcer. 3. It is prohibited for people who are allergic to any component of this product.

1. The product shall not be taken continuously for more than 5 days. Long-term or heavy use may lead to damage of hematopoietic system and liver and kidney function, and even lead to necrosis of liver cells in severe cases. 2. Long-term use can lead to dependence and tolerance. 3. It is ineffective for all kinds of traumatic pain and visceral smooth muscle colic. 4. Aminopyrine acts with food under gastric acid and can form carcinogenic nitroso compounds, especially nitrosamines, so it has potential carcinogenicity. 5. Drinking alcohol while taking this product will increase the adverse reaction of this product. 6. Use with caution in cases of alcoholism, liver disease or viral hepatitis, where there is a risk of increased liver toxicity; Renal insufficiency, although occasionally used, may increase the risk of renal toxicity if used in large quantities over a long period of time.

[Special population medication] Children:

It should be avoided in children under 3 years old and newborns due to liver and kidney dysfunction. Not recommended for children over 3 years of age.



Precautions during pregnancy and lactation:

The acetaminophen and caffeine in this product may cause adverse effects on the fetus, which is toxic to the embryo and teratogenic. Can be secreted through milk, so pregnant women and lactating women forbidden.



Precautions for the elderly:

It should be used with caution in elderly patients due to decreased liver and kidney function.

[Drug interaction] 1. When used together with chloramphenicol, it can enhance the toxicity of the latter. 2. Long-term use in large quantities with aspirin, other salicylate preparations or other non-steroidal anti-inflammatory drugs significantly increases the risk of renal toxicity. 3. Isoniazid and methalamine can promote the effect of caffeine, increasing the concentration in the brain tissue of the latter by 55%, while decreasing the concentration in the liver and kidney to some extent. 4. Oral contraceptives may slow caffeine clearance. 5. When acetaminophen is used in combination with the antiviral drug zidovudine, it can increase its toxicity and should be avoided simultaneously. 6. When used together with anticoagulants, adrenal corticosteroids, glucocorticoids, cyclosporine, digitalis side, quinidine, griseofulvin, etc., drug interaction can affect the efficacy.

[Pharmacological effect] This product is an antipyretic and analgesic drug. Aminopyrine and acetaminophen can inhibit the synthesis and release of prostaglandin in the hypothalamus and restore the normal responsiveness of sensory neurons in the thermoregulation center, thus playing an antipyretic role. It also plays an analgesic role by inhibiting the synthesis and release of prostaglandin (PGE) bradykinin and histamine. Aminopyrine also inhibits the synthesis and release of prostaglandin in inflammatory local tissues, stabilizes lysosomal membrane, affects the phagocytosis of phagocytes and plays an anti-inflammatory role. Because of the central nervous excitant, coffee can stimulate the cerebral cortex, improve the sensitivity to the outside world, and has the contraction of cerebrovascular, strengthen the first two drugs to relieve the effect of headache.

Store sealed and in a dry place.

Specification Aminopyrine 0.15g, acetaminophen 0.127g, caffeine 50mg

[Packaging Specifications] Aluminum foam caps, 3 plates per box, 6 tablets per board, Aluminum foam caps, 2 plates per box, 6 tablets per board

[Validity] is tentatively fixed for 24 months

[Approval Number] National medicine approval H21024067




FAQ
1.who are we?
We are based in Fujian, China, start from 2000,sell to North America(40.00%),Southeast Asia(25.00%),Western Europe(25.00%),Africa(10.00%).There are total about 50 people in our office.

2. how can we guarantee quality?
Always a pre-production sample before mass production;
Always final Inspection before shipment;

3.what can you buy from us?
Pharmaceutical production lines,Intermediates,APIs,Finished Drug Preparations & Vaccines.

4. why should you buy from us not from other suppliers?
We have our own manufacture factories and one professional sales team working for the clients all over the world.

5. what services can we provide?
Accepted Delivery Terms: FOB,CIF,EXW,DDP,Express Delivery;
Accepted Payment Currency:USD,EUR,CAD,AUD,GBP,CNY;
Accepted Payment Type: T/T,L/C,PayPal,Western Union;
Language Spoken:English,Chinese,Japanese

Our Ddvantage:
1. Quick delivery
2. Online payment
3. Quality assurance
4. Welcome big order
5. After-sales service 24 hours
6. Competitive advantage products
7. Our value information is "Quality is our culture"
8. Work with us to provide you with secure funds, your business is securely protected, our advantages

Our Service
a)  Free amples can be provided.
b) Guide customers through professional technology and teach them how to use our products after sale
c) Determine the lowest price of high-quality products
1. Skilled experience: Our company is a leading manufacturer of professional production in China pharmaceutical field for many years.
2. The highest quality: to ensure high quality, once any problems are found, the package will be re-shipped for you.
3. Safe transportation: by air express (FedEx, UPS, DHL, EMS). It is recommended that you choose the most professional freight forwarder.
4. Fast delivery: We have stock, so once payment is received, we can deliver quickly.
5. Quality service: We will provide you with enthusiastic after-sales service. If you have any questions, we will reply to youwithin 24 hours.
6. Competitive price: discounts will be obtained when making large orders.

Our Manufacture Factory
Fuzhou FUL Fluid Equipment & Pharmaceutical Co., Ltd is a comprehensive enterprise which integrates R & D, production and construction of pharmaceutical production equipments, development and transfer of biotechnology, and cooperative production and sales of drugs and vaccines. The self-developed pharmaceutical production equipment branded FUL has been put into operation in many well-known pharmaceutical enterprises such as SINOPHARM, CSPC and also cooperates with many well-known pharmaceutical enterprises in production and sales, including pharmaceutical intermediates, APIs and finished drug preparations.

Fuzhou FUL Fluid Equipment & Pharmaceutical Co., Ltd business radiates to all levels, including direct supply cooperation with government departments and industry representatives, as well as establishing supply cooperation relationship with retail industry. We supply high quality, safe and effective medicines and medical equipment to governments, hospitals, clinics and licensed pharmacies in different countries with timely and effective services at reasonable prices.

At present Fuzhou FUL Fluid Equipment & Pharmaceutical Co., Ltd has the SINOPHARM authorization to sell its intermediates and APIs,and has the authorizations of CSPC & HUABEI PHARM sell its finished drug preparations;then FUL is the only manufacture in China which can supply the complete service from pharmaceutical produciton lines,intermediates and APIs to finished drug preparations and vaccines.Then we are seeking the professional pharmaceutical enterprices to work together for further cooperations.
 

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