Indometacin Suppositories for Non Steroidal Anti Inflammatory Drugs

• Transport Package: Box
• Specification: 100mg*10tab/box
• Trademark: FUL
• Origin: China
• Model NO.: FC129
• Production Capacity: 10000PCS/ Month

Product Description

Item Name:Indometacin suppositories
Molecular formula:C₁₉H₁₆ClNO₄

Item Description

Item nanme:Indometacin suppositories
Item character: This product is white

Indication:
This product is a non steroidal anti-inflammatory drug with analgesic and antipyretic effects. It is used for rheumatoid arthritis, rheumatoid arthritis, tumor pain relief and tumor blood disease antipyretic.

Item specifications: 100mg*10tab/box

Usage and dosage:For anal administration, first tear a bolt along the incision of the edge of the aluminum foil, then tear it apart along the top of the two layers of aluminum foil, take out the bolt particles and plug it into the anus. One at a time, into the anus, once a day or as directed by the doctor

Adverse reactions
The adverse reactions of this product were more than ibuprofen, naproxen and diclofenac. Nervous system: headache, dizziness, anxiety and insomnia about 10% - 25%, severe cases can have mental behavior disorders or convulsions, etc; Kidney: hematuria, edema and renal insufficiency are common in the elderly; The most serious type of rash was erythema multiforme (Steven Johnson syndrome); Aplastic anemia, leukopenia or thrombocytopenia may occur due to suppression of hematopoietic system; Allergic reaction, asthma, vascular edema and shock..

Taboo:
1. it is forbidden for allergic patients, vascular edema or bronchospasm of this product and other antipyretic analgesics.
2. it is forbidden to treat the pain during the perioperative period of CABG.
3. patients with gastrointestinal bleeding or perforation history after the application of NSAIDs are prohibited.
4. patients with active gastrointestinal ulcer / bleeding, or patients who have had previous recurrent ulcer / bleeding, are forbidden.
5. severe heart failure patients are forbidden.
6. patients who have asthma, urticaria or allergic reactions after taking aspirin or other NSAIDs are prohibited.
7. this product is metabolized by the liver and excreted by the kidney has certain toxicity to the liver and kidney. Therefore, the liver and kidney should be used or disabled carefully when the function is not complete.
8. for epilepsy, Parkinson's disease and mental disease, this product can aggravate the disease and should be used carefully.
9. because this product can prolong the bleeding time and aggravate the bleeding tendency, hemophilia and other bleeding diseases should be used carefully. In addition, this product has inhibitory effect on hematopoietic system, and patients with aplastic anemia should be cautious to use it

Matters needing attention:
1. Avoid the combination with other NSAIDs, including selective COX-2 inhibitors.
2. According to the need of controlling symptoms, the use of the lowest effective dose in the shortest treatment time can minimize the adverse reactions.
3. Gastrointestinal bleeding, ulcer and perforation may occur at any time during the treatment with all NSAIDs, and the risk may be fatal. These adverse reactions may or may not be accompanied by warning symptoms, regardless of whether the patient has a history of gastrointestinal adverse reactions or serious gastrointestinal events. Patients with previous gastrointestinal history (ulcerative colitis, Crohn's disease) should be cautious in the use of non steroidal anti-inflammatory drugs, so as not to worsen the disease. The drug should be stopped when gastrointestinal bleeding or ulcer occurs. The risk of adverse reactions, especially gastrointestinal bleeding and perforation, can be fatal in elderly patients.
4. Clinical trials of COX-2 selective or non selective NSAIDs lasting for 3 years show that this product may increase the risk of serious cardiovascular thrombotic adverse events, myocardial infarction and stroke, and its risk may be fatal. All NSAIDs, including COX-2 selective or non selective drugs, may have similar risks. Patients with cardiovascular disease or cardiovascular risk factors have a higher risk. Doctors and patients should be alert to such events even if they have no previous cardiovascular symptoms. The patient should be informed of the symptoms and / or signs of severe cardiovascular safety and the steps to be taken if they occur.
Patients should be alert to symptoms and signs such as chest pain, shortness of breath, weakness, vagueness of speech, and seek medical help immediately after any of the above symptoms or signs occur.
5. Like all non steroidal anti-inflammatory drugs (NSAIDs), this product can cause new onset hypertension or aggravate the existing symptoms of hypertension, any of which can increase the incidence of cardiovascular events. Non steroidal anti-inflammatory drugs (nsalds) may affect the efficacy of thiazides or loop diuretics. Patients with hypertension should be cautious in the use of non steroidal anti-inflammatory drugs (NSAIDs), including this product. Blood pressure should be closely monitored at the beginning and throughout the treatment.
6. patients with hypertension and heart failure * such as fluid retention and edema should be cautious.
7. NSAIDs, including this product, may cause fatal and serious skin adverse reactions, such as exfoliative dermatitis, Stevens Johnson syndrome (SJS) and toxic epidermal necrolysis (ten). These serious events can occur without warning. Patients should be informed of the symptoms and signs of severe skin reactions, and discontinue the product when skin rashes or other signs of allergic reactions appear for the first time.
8. Interference to diagnosis: This product can cause transient increase of serum transaminase, decrease of serum uric acid content and increase of uric acid content.
9. Regular follow-up examination should be carried out during medication: 1) hemogram and liver and kidney function; 2) Long term drug users should have regular ophthalmic examination. This product can lead to corneal deposition and retinal changes (including macular disease). In case of blurred vision, ophthalmic examination should be done immediately.

Medication for pregnant and lactating women:
1. this product can block the fetal artery catheter and cause persistent pulmonary hypertension 3 months after pregnancy. Pregnant women are forbidden.
2. this product can be discharged from milk and can cause toxic and side effects to infants. Lactation women are prohibited.

FAQ
1.who are we?
We are based in Fujian, China, start from 2000,sell to North America(40.00%),Southeast Asia(25.00%),Western Europe(25.00%),Africa(10.00%).There are total about 50 people in our office.

2. how can we guarantee quality?
Always a pre-production sample before mass production;
Always final Inspection before shipment;

3.what can you buy from us?
Pharmaceutical production lines,Intermediates,APIs,Finished Drug Preparations & Vaccines.

4. why should you buy from us not from other suppliers?
We have our own manufacture factories and one professional sales team working for the clients all over the world.

5. what services can we provide?
Accepted Delivery Terms: FOB,CIF,EXW,DDP,Express Delivery;
Accepted Payment Currency:USD,EUR,CAD,AUD,GBP,CNY;
Accepted Payment Type: T/T,L/C,PayPal,Western Union;
Language Spoken:English,Chinese,Japanese

Our Ddvantage:
1. Quick delivery
2. Online payment
3. Quality assurance
4. Welcome big order
5. After-sales service 24 hours
6. Competitive advantage products
7. Our value information is "Quality is our culture"
8. Work with us to provide you with secure funds, your business is securely protected, our advantages

Our Service
a)  Free amples can be provided.
b) Guide customers through professional technology and teach them how to use our products after sale
c) Determine the lowest price of high-quality products
1. Skilled experience: Our company is a leading manufacturer of professional production in China pharmaceutical field for many years.
2. The highest quality: to ensure high quality, once any problems are found, the package will be re-shipped for you.
3. Safe transportation: by air express (FedEx, UPS, DHL, EMS). It is recommended that you choose the most professional freight forwarder.
4. Fast delivery: We have stock, so once payment is received, we can deliver quickly.
5. Quality service: We will provide you with enthusiastic after-sales service. If you have any questions, we will reply to youwithin 24 hours.
6. Competitive price: discounts will be obtained when making large orders.

Our Manufacture Factory
Fuzhou FUL Fluid Equipment & Pharmaceutical Co., Ltd is a comprehensive enterprise which integrates R & D, production and construction of pharmaceutical production equipments, development and transfer of biotechnology, and cooperative production and sales of drugs and vaccines. The self-developed pharmaceutical production equipment branded FUL has been put into operation in many well-known pharmaceutical enterprises , CSPC and also cooperates with many well-known pharmaceutical enterprises in production and sales, including pharmaceutical intermediates, APIs and finished drug preparations.

Fuzhou FUL Fluid Equipment & Pharmaceutical Co., Ltd business radiates to all levels, including direct supply cooperation with government departments and industry representatives, as well as establishing supply cooperation relationship with retail industry. We supply high quality, safe and effective medicines and medical equipment to governments, hospitals, clinics and licensed pharmacies in different countries with timely and effective services at reasonable prices.

At present Fuzhou FUL Fluid Equipment & Pharmaceutical Co., Ltd has the  authorization to sell its intermediates and APIs,and has the authorizations of CSPC & HUABEI PHARM sell its finished drug preparations;then FUL is the only manufacture in China which can supply the complete service from pharmaceutical produciton lines,intermediates and APIs to finished drug preparations and vaccines.Then we are seeking the professional pharmaceutical enterprices to work together for further cooperations.




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