Item nanme:Risperidone orally disintegrating tablets Item character:The product is white
Indication: 1. It is used to treat the symptoms of acute and chronic schizophrenia and other kinds of psychotic state. 2. For patients with effective treatment in acute phase, risperidone can continue to play its clinical efficacy in maintenance phase. 3. It can be used to treat manic episode of bipolar disorder, which is characterized by high emotion, exaggeration or irritability, reduced sleep requirements, faster speech speed, distraction or low judgment (including disorder or extreme behavior).
Item specifications:1mg*20tab/box
Usage and dosage:1. For schizophrenic patients who use other antipsychotics instead of this product: at the beginning of use, the original antipsychotics should be gradually stopped. If the patient originally used a long-acting antipsychotic, risperidone can be used instead of the next course of treatment. Whether the drugs used to treat Parkinson's syndrome need to be continued or not should be reevaluated regularly. Once daily or twice daily. The initial dose was 1 mg, and the dose was gradually increased to 2-4 mg per day in about one week, and 4-6 mg per day in the second week. After that, the dose can be kept unchanged or further adjusted according to personal conditions. Generally, the optimal dose is 2-6mg per day. The daily dose is usually less than 10mg. 2. The recommended starting dose for manic episode of bipolar disorder is 1-2mg once a day, which can be adjusted according to individual needs. The range of dose increase was 1-2 mg per day. The dose increase was carried out at least every other day or more days. The ideal dose for most patients is 2-6mg per day. During all symptomatic treatment, the need for continued use of this product should be continuously evaluated. 3. The ability of antipsychotics clearance in patients with liver and kidney dysfunction was lower than that in healthy adults; The plasma concentration of free risperidone was increased in patients with liver dysfunction. No matter what indication, the initial and maintenance dose of patients with renal or liver dysfunction should be halved, and the dose adjustment should be slowed down. Such patients should be careful when using this product.
Adverse reactions 1. The common adverse reactions related to taking this product are insomnia, anxiety, headache, dizziness and dry mouth.
2. The rare adverse reactions are drowsiness, fatigue, attention loss, constipation, dyspepsia, nausea, vomiting, abdominal pain, blurred vision, priapism, erectile dysfunction, ejaculation weakness, sexual apathy, urinary incontinence, rhinitis, rash and other allergic reactions.
3. May cause extrapyramidal symptoms, such as: muscle tension, tremor, stiffness, salivation, bradykinesia, akathisia, acute dystonia. It can be eliminated by reducing the dose or giving anti Parkinson's syndrome drugs.
4. Occasionally (postural) hypotension, (reflex) tachycardia or hypertension will appear.
5. There will be weight gain, edema and liver enzyme levels
6. Occasionally, water poisoning is caused by thirst or SIADH.
7. It can cause the increase of prolactin concentration in plasma, and its related symptoms are: galactorrhea, male female breast, menstrual disorders, amenorrhea.
8. Tardive dyskinesia, malignant symptom group, body temperature disorder and epileptic seizure were occasionally seen.
9. One case of mild neutrophil and / or platelet count decrease was reported
Taboo: It is not allowed to be allergic to this product.
Matters needing attention: 1. people with cardiovascular diseases (such as heart failure, myocardial infarction, conduction abnormality, dehydration, blood loss and cerebrovascular disease) should be careful to use, starting from small dose and increasing dose gradually.
2. because this product has α Receptor block activity, so hypotension (posture) will occur in the early stage of drug use and when the rate of administration is too fast, and reduction should be considered.
3. similar to other drugs with dopamine receptor antagonists, it causes delayed motor disorder, which is characterized by rhythmic and random movement, mainly in tongue and face. If there is a late motor disorder, stop taking all antipsychotics.
4. it has been reported that the classic antipsychotics may have malignant symptoms, characterized by high fever, muscle stiffness, trembling, consciousness change and the rise of creatine phosphokinase level. All antipsychotics, including this product, should be discontinued at this time.
5. patients with Parkinson's syndrome should use this product carefully, because in theory, the drug can cause the disease to deteriorate.
6. classic antipsychotics can reduce the seizure threshold of epilepsy, so patients with epilepsy should still use this product carefully.
7. patients taking this product should avoid eating too much to avoid getting fat.
8. in view of the effect of this product on the central nervous system, it should be taken carefully when taking the same medicine as other drugs acting on the central nervous system.
9. this product has an impact on activities requiring alertness. Therefore, it is recommended that patients should not drive cars or operate machines until they are aware of the patient's sensitivity to the drug.
Medication for pregnant and lactating women: 1. It is not clear whether it is safe for pregnant women to take this product. 2. Animal experiments show that risperidone has no direct toxicity to reproduction and teratogenicity. However, pregnant women should not take this product unless the benefits outweigh the possible risks. 3. It is not clear whether the product will be excreted through human milk. Animal experiments show that risperidone and 9-hydroxy-risperidone will be excreted through animal milk. Therefore, women taking this product should not breastfeed.
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