Item nanme:Amlodipine besylate tablets Item character:This product is white
Indication: 1. Hypertension
This product is suitable for the treatment of hypertension. It can be used alone or in combination with other antihypertensive drugs.
2. Coronary heart disease (CAD)
chronic stable angina
This product is suitable for symptomatic treatment of chronic stable angina pectoris. It can be used alone or in combination with other anti angina drugs.
Vasospasm angina pectoris (Prinzmetal's or variant angina pectoris)
This product is suitable for the treatment of confirmed or suspected vasospasm angina pectoris. It can be used alone or in combination with other anti angina drugs.
Coronary heart disease confirmed by angiography
This product can reduce the risk of hospitalization due to angina pectoris and the risk of coronary artery reconstruction in patients with coronary heart disease confirmed by angiography but with ejection fraction ≥ 40% and no heart failure.
Item specifications: 5mg*14tab/box
Usage and dosage:Adult: usually, the initial dose of this product for the treatment of hypertension is 5mg, once a day, and the maximum dose is 10mg, once a day. For patients with small stature, weakness, old age, or liver dysfunction, the initial dose is 2.5mg, once a day; this dose can also be used in combination with other antihypertensive drugs.
The dose adjustment should be based on the individual response of patients. The general dose adjustment should start after 7-14 days. If clinical needs, in the case of close monitoring of patients, the dose can be adjusted more quickly.
The recommended dose for the treatment of chronic stable or vasospasm angina pectoris is 5-10mg once a day. For the elderly and patients with liver dysfunction, a lower dose is recommended. The effective dose for most patients is 10mg once a day.
The recommended dose for the treatment of coronary heart disease is 5-10mg once a day. In clinical studies, most patients need a dose of 10 mg / day (see [clinical trials]).
Adverse reactions 1. hypotension
Symptomatic hypotension may occur, especially in patients with severe aortic stenosis. Because the vasodilation of this product is gradually produced, the incidence of acute hypotension after taking this product is rarely reported.
2. angina aggravation or myocardial infarction
In a few patients, especially those with severe coronary artery occlusion, angina may deteriorate or acute myocardial infarction may occur when amlodipine benzenesulfonate is used or increased dosage.
3. β - receptor blocker stopping
The sudden stop of β - blocker may be dangerous. As amlodipine is not a β - blocker, it can not effectively protect the danger of β - blocker stopping; any β - blocker should stop drug gradually.
4. use of patients with liver function impairment
Because the product is metabolized in large quantities through the liver and the plasma clearance half-life (t1/2) of patients with liver dysfunction is 56 hours, it should be increased slowly when used in patients with severe liver dysfunction.
Medication for pregnant and lactating women: Pregnancy classification C (FDA classification)
There was no sufficient and well controlled study in pregnant women. Amlodipine can only be used during pregnancy if the potential benefits exceed the potential risk to the fetus.
No teratogenic or other embryo / fetal toxicity was found when pregnant rats and rabbits received amlodipine 10 mg / kg / day (based on mg/m[sup]2[/sup] conversion, respectively, 8 times of the maximum recommended dose of 10 mg and 23 times of the maximum recommended dose of human beings [calculated according to the weight of the patient] respectively). However, in rats treated with amlodipine maleate (10 mg amlodipine / kg/ day) for 14 days before mating, during the entire mating and pregnancy, a significant decrease in the number of nests (about 50 per cent) and a significant increase in the number of deaths in the uterus (about 5 times) were observed. It has been proved that amlodipine maleate can prolong the pregnancy and delivery period of rats at this dose.
It is not known whether the product can be secreted through milk, and the lactation women taking medicine should stop breastfeeding.
FAQ 1.who are we? We are based in Fujian, China, start from 2000,sell to North America(40.00%),Southeast Asia(25.00%),Western Europe(25.00%),Africa(10.00%).There are total about 50 people in our office.
2. how can we guarantee quality? Always a pre-production sample before mass production; Always final Inspection before shipment;
3.what can you buy from us? Pharmaceutical production lines,Intermediates,APIs,Finished Drug Preparations & Vaccines.
4. why should you buy from us not from other suppliers? We have our own manufacture factories and one professional sales team working for the clients all over the world.
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Our Service a) Free amples can be provided. b) Guide customers through professional technology and teach them how to use our products after sale c) Determine the lowest price of high-quality products 1. Skilled experience: Our company is a leading manufacturer of professional production in Chinapharmaceutical field for manyyears. 2. The highest quality: to ensure high quality, once any problems are found, the package will be re-shipped for you. 3. Safe transportation: by air express (FedEx, UPS, DHL, EMS). It is recommended that you choose the most professional freightforwarder. 4. Fast delivery: We have stock, so once payment is received, we can deliver quickly. 5. Quality service: We will provide you with enthusiastic after-sales service. If you have any questions, we will reply to youwithin 24 hours. 6. Competitive price: discounts will be obtained when making large orders.
Our Manufacture Factory Fuzhou FUL Fluid Equipment & Pharmaceutical Co., Ltd is a comprehensive enterprise which integrates R & D, production and construction of pharmaceutical production equipments, development and transfer of biotechnology, and cooperative production and sales of drugs and vaccines. The self-developed pharmaceutical production equipment branded FUL has been put into operation in many well-known pharmaceutical enterprises such as SINOPHARM, CSPC and also cooperates with many well-known pharmaceutical enterprises in production and sales, including pharmaceutical intermediates, APIs and finished drug preparations.
Fuzhou FUL Fluid Equipment & Pharmaceutical Co., Ltd business radiates to all levels, including direct supply cooperation with government departments and industry representatives, as well as establishing supply cooperation relationship with retail industry. We supply high quality, safe and effective medicines and medical equipment to governments, hospitals, clinics and licensed pharmacies in different countries with timely and effective services at reasonable prices.
At present Fuzhou FUL Fluid Equipment & Pharmaceutical Co., Ltd has the SINOPHARM authorization to sell its intermediates and APIs,and has the authorizations of CSPC & HUABEI PHARM sell its finished drug preparations;then FUL is the only manufacture in China which can supply the complete service from pharmaceutical produciton lines,intermediates and APIs to finished drug preparations and vaccines.Then we are seeking the professional pharmaceutical enterprices to work together for further cooperations.
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