Levothyroxine Sodium Tablets for Treatment of Nontoxic Goiter

• Transport Package: Box
• Specification: 50ug*100tab/box
• Trademark: FUL
• Origin: China
• Model NO.: FC130
• Production Capacity: 10000PCS/ Month

Product Description

Item Name:Levothyroxine sodium tablets
Molecular formula:C₁₅H₂₅I₄NNaO₄·xH₂O

Item Description

Item nanme:Levothyroxine sodium tablets
Item character: This product is white

Indication:
1. Treatment of nontoxic goiter (normal thyroid function).
2. To prevent recurrence of goiter after thyroidectomy.
3. Alternative treatment of hypothyroidism.
4. Auxiliary treatment of hyperthyroidism with antithyroid drugs.
5. Suppression therapy after thyroid cancer operation.
6. Thyroid suppression test.

Item specifications: 50ug*100tab/box

Usage and dosage:The recommended dose in this item is a general principle, and the individual daily dose of patients should be determined according to the results of laboratory and clinical examination.
Because the level of T4 and FT4 will increase in many patients, the basic concentration of serum thyroid stimulating hormone is a reliable basis to determine the treatment.
In addition to the rapid dose increase is very important for newborns, the general thyroid hormone therapy should start with low dose, and gradually increase the dose every 2-4 weeks until reaching the full dose.
For elderly patients, patients with coronary heart disease and patients with severe or long-term hypothyroidism, special attention should be paid to the beginning of thyroid hormone therapy, and a lower initial dose (e.g. 12.5 mg / kg) should be selected μ 5 g / day) and slowly increase the dosage in a long time interval (e.g. 12.5 g / day every two weeks) μ G / day). In addition, it should be noted that if the final maintenance dose is lower than the optimal dose, the TSH level can not be completely corrected.
Experience has shown that low dose administration is effective in patients with light weight and with large nodular goiter.
Daily dose of levothyroxine sodium tablets
Dose 50 μ G dosage 100 μ Dosage and Administration
Goiter (normal thyroid function) 75-200 μ G 3 / 2-4 tablets 3 / 4-2 tablets once a day
Prevention of Thyroid Recurrence after thyroidectomy 75-200 μ G 3 / 2-4 tablets 3 / 4-2 tablets once a day
Adult hypothyroidism
-Initial dose 25-50 μ G 1 / 2-1 tablet 1 / 4-1 / 2 tablet once a day
(25-50% increase every 2-4 weeks after initial dose μ g. Until maintenance dose)
-Maintenance dose 100-200 μ G 2-4 tablets 1-2 tablets once a day
Hypothyroidism in children
-Initial dose 12.5-50 μ G 1 / 4-1 tablet 1 / 8-1 / 2 tablets once a day
-Maintenance dose 100-150 μ G / m2 body surface area 2-3 tablets / m2 body surface area 1-3 / 2 tablets / m2 body surface area once a day
Adjuvant treatment of hyperthyroidism 50-100 μ G 1-2 tablets 1 / 2-1 tablets once a day
150-300 years after thyroid cancer surgery μ G - 1.5 - 3 tablets once a day
Thyroid suppression test 200 μ G - 2 tablets once daily
Suppression therapy for left thyroid cancer (recommended daily dose 150-300) μ g) In order to accurately adjust the dosage of patients, 50 μ G can be used with other high dose tablets.
Levothyroxine sodium tablets should be taken half an hour before breakfast on an empty stomach with a daily dose of appropriate liquid (such as half a cup of water).
Infants should take the full dose of this product at least 30 minutes before the first meal of the day. The tablets can be mashed into suspension with proper amount of water. But remember that this step should be done temporarily before taking medicine. The obtained drug suspension can be administered with appropriate liquid.
Under normal circumstances, patients with hypothyroidism, patients after partial or total thyroidectomy, and patients after removal of goiter to prevent recurrence of goiter should take medicine for life. When combined with this drug in the treatment of hyperthyroidism, the administration cycle of this drug should be the same as that of antithyroid drugs.
For benign goiter, a course of 6 months to 2 years is necessary. In order to avoid the recurrence of goiter, it is recommended to use low-dose iodine (100-200 mg / kg) after the goiter shrinks μ g) If these drugs are not enough to relieve goiter, surgery and radioiodine therapy should be considered.

Adverse reactions
If we take the medicine according to the doctor's advice and monitor the clinical and laboratory indexes, there will be no adverse reactions. If the individual's tolerated dose is exceeded or overdosed, especially due to the rapid dose increase at the beginning of treatment, the following clinical symptoms of hyperthyroidism may occur, including tachycardia, palpitation, arrhythmia, angina pectoris, headache, muscle weakness and spasm, flushing, fever, vomiting, menstrual disorders, pseudoencephaloma, tremor, restlessness, insomnia, hyperhidrosis Weight loss and diarrhea.
In these cases, the daily dose of the patient should be reduced or the drug should be stopped for a few days. Once the above symptoms disappear, the patient should carefully restart the drug treatment.
For some hypersensitive patients, allergic reactions may occur.

Taboo:
Highly sensitive to this product and its excipients.
Untreated adrenal insufficiency, pituitary insufficiency and thyrotoxicosis.
The application of this product should not start from the stage of acute myocardial infarction, acute myocarditis and acute pancarditis.
This product is not used in combination with antithyroid drugs in the treatment of hyperthyroidism during pregnancy.

Matters needing attention:
Patients should not be treated with or without treatment of the following diseases before the treatment of thyroid hormone: coronary heart disease, angina pectoris, arteriosclerosis, hypertension, hypophysis, adrenal insufficiency and autonomic high-functional thyroid tumor.
For patients with coronary heart disease, cardiac dysfunction or tachycardia, it is necessary to avoid the symptoms of hyperthyroidism caused by levothyroxine. Therefore, thyroid hormone levels should be monitored frequently in these patients.
For secondary hypothyroidism, the cause must be determined before the replacement treatment with this product. If necessary, glucocorticoid should be supplemented.
If there is suspected of autonomic high-function thyroid tumor, TRH should be performed before treatment or the anti flicker scan should be obtained.
For postmenopausal women with increased risk of hypothyroidism and osteoporosis, the left thyroxine at the level of super physiological serum should be avoided, so the thyroid function should be closely measured.
Only when anti thyroid drugs are used for hyperthyroidism, this product can be used for supplementary treatment. Otherwise, in the case of hyperthyroidism, left thyroxine should not be used alone.
Once the treatment of left thyroxine has been determined. In the case of drug replacement, it is suggested to adjust the dosage according to the clinical response and the results of the experimental examination.
This product is not allowed in rare patients with inherited galactose intolerance, Lapp lactase deficiency or glucose galactose absorption disorder.
For diabetics and patients undergoing anticoagulant treatment, see drug interactions.
Taking this product will not affect the driving and operation of the machine.

Medication for pregnant and lactating women:
In pregnancy and lactation, special attention should be paid to the continued use of thyroid hormone for treatment. The dose of this product may increase during pregnancy. So far, although pregnant women widely use this product, there is no report that this product will harm Yier. In the case of high dose of left thyroxine treatment, the amount of thyroid hormone Qin in milk during lactation is not enough to cause hyperthyroidism or TSH secretion in infants to be inhibited.
It is not suitable to combine levothyroxine with anti thyroid drugs in the treatment of hyperthyroidism during pregnancy, because the addition of levothyroxine increases the dose of anti thyroid drugs.
Different from left thyroxine, effective doses of anti thyroid drugs can pass through placenta, so it is necessary to combine with LHT treatment with higher doses of anti thyroid drugs, which may lead to hypothyroidism in fetus. Therefore, for breast-feeding women with left hyperthyroidism, they must be treated with anti thyroid drugs alone.

FAQ
1.who are we?
We are based in Fujian, China, start from 2000,sell to North America(40.00%),Southeast Asia(25.00%),Western Europe(25.00%),Africa(10.00%).There are total about 50 people in our office.

2. how can we guarantee quality?
Always a pre-production sample before mass production;
Always final Inspection before shipment;

3.what can you buy from us?
Pharmaceutical production lines,Intermediates,APIs,Finished Drug Preparations & Vaccines.

4. why should you buy from us not from other suppliers?
We have our own manufacture factories and one professional sales team working for the clients all over the world.

5. what services can we provide?
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Our Service
a)  Free amples can be provided.
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c) Determine the lowest price of high-quality products
1. Skilled experience: Our company is a leading manufacturer of professional production in China pharmaceutical field for many years.
2. The highest quality: to ensure high quality, once any problems are found, the package will be re-shipped for you.
3. Safe transportation: by air express (FedEx, UPS, DHL, EMS). It is recommended that you choose the most professional freight forwarder.
4. Fast delivery: We have stock, so once payment is received, we can deliver quickly.
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6. Competitive price: discounts will be obtained when making large orders.

Our Manufacture Factory
Fuzhou FUL Fluid Equipment & Pharmaceutical Co., Ltd is a comprehensive enterprise which integrates R & D, production and construction of pharmaceutical production equipments, development and transfer of biotechnology, and cooperative production and sales of drugs and vaccines. The self-developed pharmaceutical production equipment branded FUL has been put into operation in many well-known pharmaceutical enterprises such as SINOPHARM, CSPC and also cooperates with many well-known pharmaceutical enterprises in production and sales, including pharmaceutical intermediates, APIs and finished drug preparations.

Fuzhou FUL Fluid Equipment & Pharmaceutical Co., Ltd business radiates to all levels, including direct supply cooperation with government departments and industry representatives, as well as establishing supply cooperation relationship with retail industry. We supply high quality, safe and effective medicines and medical equipment to governments, hospitals, clinics and licensed pharmacies in different countries with timely and effective services at reasonable prices.

At present Fuzhou FUL Fluid Equipment & Pharmaceutical Co., Ltd has the SINOPHARM authorization to sell its intermediates and APIs,and has the authorizations of CSPC & HUABEI PHARM sell its finished drug preparations;then FUL is the only manufacture in China which can supply the complete service from pharmaceutical produciton lines,intermediates and APIs to finished drug preparations and vaccines.Then we are seeking the professional pharmaceutical enterprices to work together for further cooperations.




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