Sulfamethoxazole Sulfadiazine and Trimethoprim Tablets for Acute Onset of Adult Chronic Bronchitis and Acute Otitis Media

• Transport Package: Carton
• Specification: 20x15x15cm
• Trademark: FUL
• Origin: China
• Model NO.: CF051-1
• Production Capacity: 100000/Month

Product Description

[Drug name] General name: metexoprim tablet

Sulfamethoxazole Sulfadiazine and Trimethoprim Tablets

Ingredients This product is a compound preparation, each tablet contains sulfamethazole, sulfadiazine and trimethoprim

[Indications] It is mainly used for urinary tract infection, intestinal infection, acute onset of adult chronic bronchitis and acute otitis media caused by bacteria sensitive to this product.

Usage and Dosage Normal oral dosage for adults is: 2 tablets at a time, 2 times a day, double the first dose. Chronic bronchitis acute attack course of treatment at least 10 ~ 14 days; Urinary tract infection course of 7 ~ 10 days; Bacterial dysentery for 5-7 days; Acute otitis media for 10 days

[Adverse Reactions] 1. Allergic reactions are common. It can be manifested as drug eruption, and in severe cases, exudative polymorphic erythema, exfoliative dermatitis and bullous epidermolytic atrophic dermatitis can occur. Also have performance for photosensitive reaction, drug heat, joint and muscle pain, fever and other serum disease like reaction. Occasionally anaphylactic shock. 2. Neutropenia or deficiency, thrombocytopenia, occasionally may occur aplastic anemia. Patients may present with sore throat, fever, and bleeding tendencies. Hemolytic anemia and hemoglobinuria. This is more common in newborns and children than in adults after sulfonamides are used in patients with glucose-6-phosphate dehydrogenase deficiency. Hyperbilirubinemia and neonatal nuclear jaundice. Because this product and bilirubin competition protein binding site, can cause free bilirubin increase. The liver function of newborns is imperfect,

1. It is contraindicated for people allergic to sulfonamides. 2. This product is contraband in patients with megaloblastic anemia because it prevents the metabolism of folate and aggravates the deficiency of folate. 3. Pregnant women and lactating women are prohibited from using this product. 4. This product is contraindicated for infants under 2 months old. 5. People with liver and kidney function damage should not use this product.

1. Cross allergic reaction. Patients who are allergic to one sulfonamides may also be allergic to other sulfonamides. 2. Liver damage. Jaundice, liver dysfunction and acute liver necrosis may occur in severe cases. Therefore, patients with liver function impairment should avoid systemic application of sulfonamides. 3. Kidney damage. Crystalline, hematuria, and tubular uria may occur. If the application of this product course of treatment is long, the dosage of large time with sodium bicarbonate and drink more water. To prevent this adverse reaction. During the treatment, check the routine urine at least 2 ~ 3 times a week. If crystallizing urine or hematuria is found, give sodium bicarbonate and drink plenty of water until the crystallizing urine and hematuria disappear. Dehydration, shock and the use of this product in elderly patients may lead to renal damage, should be used with caution or avoid the use of this product. This product should not be used in patients with renal dysfunction. 4. Patients who are allergic to furosemide, sulfoxides, thiazide diuretics, sulfonylureas, and carbonic anhydrase inhibitors may also be allergic to sulfonamides. 5. The following conditions should be used with caution: glucose-6-phosphate dehydrogenase deficiency, hematoporphyria, folate-deficient hematologic diseases, water loss, AIDS, shock and elderly patients. 6. Attention should be paid during medication: (1) Peripheral blood examination is especially important for patients with a long course of treatment, high dose, old age, malnutrition and taking antiepileptic drugs. (2) Periodic urine examination during treatment (routine urine examination every 2-3 days) to detect crystallization urine that may occur during a long course of treatment or at high doses. (3) Liver and kidney function examination. 7. Drink plenty of water each time you take this product. During the administration, adequate water intake should be maintained, so that the adult urine volume should be maintained at least 1200ml per day. If the application of this product course of treatment is long, a large number of doses in addition to drinking water should be taken with sodium bicarbonate. 8. The concentration of free sulfonamides should be determined in the blood of severely infected patients. The concentration of free sulfonamides is 50 ~ 150μg/ mL for most infected patients (120 ~ 150μg/ mL for severely infected patients). The total sulfanilamide concentration should not exceed 200μg/ mL, such as exceeding this concentration, the incidence of adverse reactions increased. 9. Do not arbitrarily increase the dose, increase the number of medication or prolong the course of treatment to prevent accumulation of poisoning. 10. Because this product can inhibit the growth of Escherichia coli, hinder the synthesis of B vitamins in the intestine, so the use of this product for more than a week, should be given B vitamins to prevent its deficiency. 11. As a result of taking this product cause lack of folic acid, can taking folic acid supplements at the same time, the latter does not interfere with the antimicrobial activity of TMP, bacteria cannot use of folic acid has been synthesized by, if there are any signs of bone marrow suppression occurred, shall immediately stop using this product, and give 3 ~ 6 mg folic acid intramuscular injection, once a day, or medication according to need to use 2 hematopoietic function returned to normal, For long-term and excessive use of this product, high dose of folic acid can be given and prolonged course of treatment.

[Specification] Sulfamethoxazole 0.2g, sulfadiazine 0.2g, Trimethoprim 80mg

[Approval Number] National medicine approval H46020475


FAQ
1.who are we?
We are based in Fujian, China, start from 2000,sell to North America(40.00%),Southeast Asia(25.00%),Western Europe(25.00%),Africa(10.00%).There are total about 50 people in our office.

2. how can we guarantee quality?
Always a pre-production sample before mass production;
Always final Inspection before shipment;

3.what can you buy from us?
Pharmaceutical production lines,Intermediates,APIs,Finished Drug Preparations & Vaccines.

4. why should you buy from us not from other suppliers?
We have our own manufacture factories and one professional sales team working for the clients all over the world.

5. what services can we provide?
Accepted Delivery Terms: FOB,CIF,EXW,DDP,Express Delivery;
Accepted Payment Currency:USD,EUR,CAD,AUD,GBP,CNY;
Accepted Payment Type: T/T,L/C,PayPal,Western Union;
Language Spoken:English,Chinese,Japanese

Our Ddvantage:
1. Quick delivery
2. Online payment
3. Quality assurance
4. Welcome big order
5. After-sales service 24 hours
6. Competitive advantage products
7. Our value information is "Quality is our culture"
8. Work with us to provide you with secure funds, your business is securely protected, our advantages

Our Service
a)  Free amples can be provided.
b) Guide customers through professional technology and teach them how to use our products after sale
c) Determine the lowest price of high-quality products
1. Skilled experience: Our company is a leading manufacturer of professional production in China pharmaceutical field for many years.
2. The highest quality: to ensure high quality, once any problems are found, the package will be re-shipped for you.
3. Safe transportation: by air express (FedEx, UPS, DHL, EMS). It is recommended that you choose the most professional freight forwarder.
4. Fast delivery: We have stock, so once payment is received, we can deliver quickly.
5. Quality service: We will provide you with enthusiastic after-sales service. If you have any questions, we will reply to youwithin 24 hours.
6. Competitive price: discounts will be obtained when making large orders.

Our Manufacture Factory
Fuzhou FUL Fluid Equipment & Pharmaceutical Co., Ltd is a comprehensive enterprise which integrates R & D, production and construction of pharmaceutical production equipments, development and transfer of biotechnology, and cooperative production and sales of drugs and vaccines. The self-developed pharmaceutical production equipment branded FUL has been put into operation in many well-known pharmaceutical enterprises such as SINOPHARM, CSPC and also cooperates with many well-known pharmaceutical enterprises in production and sales, including pharmaceutical intermediates, APIs and finished drug preparations.

Fuzhou FUL Fluid Equipment & Pharmaceutical Co., Ltd business radiates to all levels, including direct supply cooperation with government departments and industry representatives, as well as establishing supply cooperation relationship with retail industry. We supply high quality, safe and effective medicines and medical equipment to governments, hospitals, clinics and licensed pharmacies in different countries with timely and effective services at reasonable prices.

At present Fuzhou FUL Fluid Equipment & Pharmaceutical Co., Ltd has the SINOPHARM authorization to sell its intermediates and APIs,and has the authorizations of CSPC & HUABEI PHARM sell its finished drug preparations;then FUL is the only manufacture in China which can supply the complete service from pharmaceutical produciton lines,intermediates and APIs to finished drug preparations and vaccines.Then we are seeking the professional pharmaceutical enterprices to work together for further cooperations.
 

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