Isosorbide Mononitrate Sustained Release Tablets Treatment of Chronic Heart Failure

• Customization: Available
• Name: Isosorbide Mononitrate Sustained Release Tablets
• Transport Package: Box
• Model NO.: FC021-01
• Trademark: FUL
• Origin: China
• Production Capacity: 10000PCS/ Month

Product Description

Item Name: Isosorbide Mononitrate Sustained Release Tablets
Molecular formula:C₆H₉NO₆

Item Description

Item nanme: Isosorbide Mononitrate Sustained Release Tablets
Item character:The goods is white

Indication:
Prevention and long-term treatment of angina (cardiac pain caused by coronary artery disease);
Treatment of chronic heart failure with digitalis and/or diuretics.

Item specifications:20mg*48tab/box

Usage and dosage:Usage: This product should be swallowed whole with water.
Dosage: Unless otherwise prescribed by your physician, take the recommended dosage as follows:
One tablet a day (equivalent to 40mg 5-isosorbide mononitrate).If necessary, the dose can be increased to one tablet twice a day (equivalent to 80mg 5-isosorbide mononitrate).
To make full use of the drug, when the dosage is "one tablet once, twice a day", the second dose should be taken within 6 hours after the first dose.
Follow your doctor's instructions for the course of treatment.
If you forget to take the medicine, continue to take the normal dose the next time you take it, and do not cumulatively take a double dose.

Adverse reactions
Headaches (so-called nitrate headaches) often occur at the beginning of the treatment and usually disappear after a few days of continued use.
When initially administered and at increased doses, blood pressure is often bleeded and/or postural hypotension is associated with increased reflex pulse rate and a feeling of fatigue and dizziness.
Malignancy, vomiting, transient skin redness, and skin allergies are rare.
Rarely severe hypotension exacerbates angina symptoms.
Fatigue, occasional arrhythmias, bradycardia, and syncope have been reported occasionally.
Epidermal exfoliative dermatitis (inflammatory skin reaction) may occur in some cases.
Drug resistance and cross-resistance to other nitro compounds have been reported.Therefore, to prevent the loss or weakening of efficacy, high doses should be avoided.
When you experience any of these adverse reactions, please notify your doctor to determine the severity of the reactions and take appropriate measures.
If an allergy occurs, you should not take this product again.
Notify your physician or pharmacist when you notice any adverse reactions not mentioned above.
Note: Transient arterial hypoxia may occur after taking this product because of the relative redistribution of blood flow into the alveolar area of insufficient ventilation.In patients with coronary artery disease, this leads to myocardial ischemia

Taboo:
This product is prohibited in persons allergic to nitro-compounds.
It is forbidden in patients with acute circulatory failure (shock, circulatory collapse).
This product is disabled in patients with cardiogenic shock (intra-aortic counterpulsation or positive muscle strength not sufficient for left ventricular end-diastolic pressure).
It is forbidden in patients with severe hypotension (systolic blood pressure resists 90 mmHg).
Simultaneous u(trade name:  VIAFRA) is prohibited, because  does not enhance the hypotensive effect of this product.

Matters needing attention:
Take this product with special care when the patient has the following symptoms:
Hypertrophic obstructive cardiomyopathy, constrictive pericarditis, and pericardial tamponade.
Low filling pressure, such as acute heart attack (left ventricular failure).Systolic blood pressure should be avoided below 90 mmHg.
Aortic and/or mitral stenosis.
Hypotension leads to a tendency to circulatory disorders (postural circulatory disorders).
Diseases associated with increased intracranial pressure (to date, further increases in intracranial pressure have been seen only after intravenous administration of high doses of nitroglycerin).
This product is not suitable for the treatment of acute angina or heart attack.
Impact on driving vehicle and machine operation:
Even if prescribed, the drug can affect responsiveness when driving a vehicle, operating a machine, and working without proper safety measures.This effect is further enhanced by increasing doses, changing medications, and alcohol use.

Medication for pregnant and lactating women:
Although animal studies have shown that isosorbide mononitrate does not harm embryos, due to insufficient experience in the use of this drug in pregnant and breast-feeding women, careful trade-offs should be made after use.

FAQ
1.who are we?
We are based in Fujian, China, start from 2000,sell to North America(40.00%),Southeast Asia(25.00%),Western Europe(25.00%),Africa(10.00%).There are total about 50 people in our office.

2. how can we guarantee quality?
Always a pre-production sample before mass production;
Always final Inspection before shipment;

3.what can you buy from us?
Pharmaceutical production lines,Intermediates,APIs,Finished Drug Preparations & Vaccines.

4. why should you buy from us not from other suppliers?
We have our own manufacture factories and one professional sales team working for the clients all over the world.

5. what services can we provide?
Accepted Delivery Terms: FOB,CIF,EXW,DDP,Express Delivery;
Accepted Payment Currency:USD,EUR,CAD,AUD,GBP,CNY;
Accepted Payment Type: T/T,L/C,PayPal,Western Union;
Language Spoken:English,Chinese,Japanese

Our Ddvantage:
1. Quick delivery
2. Online payment
3. Quality assurance
4. Welcome big order
5. After-sales service 24 hours
6. Competitive advantage products
7. Our value information is "Quality is our culture"
8. Work with us to provide you with secure funds, your business is securely protected, our advantages

Our Service
a)  Free amples can be provided.
b) Guide customers through professional technology and teach them how to use our products after sale
c) Determine the lowest price of high-quality products
1. Skilled experience: Our company is a leading manufacturer of professional production in China pharmaceutical field for many years.
2. The highest quality: to ensure high quality, once any problems are found, the package will be re-shipped for you.
3. Safe transportation: by air express (FedEx, UPS, DHL, EMS). It is recommended that you choose the most professional freight forwarder.
4. Fast delivery: We have stock, so once payment is received, we can deliver quickly.
5. Quality service: We will provide you with enthusiastic after-sales service. If you have any questions, we will reply to youwithin 24 hours.
6. Competitive price: discounts will be obtained when making large orders.

Our Manufacture Factory
Fuzhou FUL Fluid Equipment & Pharmaceutical Co., Ltd is a comprehensive enterprise which integrates R & D, production and construction of pharmaceutical production equipments, development and transfer of biotechnology, and cooperative production and sales of drugs and vaccines. The self-developed pharmaceutical production equipment branded FUL has been put into operation in many well-known pharmaceutical enterprises , CSPC and also cooperates with many well-known pharmaceutical enterprises in production and sales, including pharmaceutical intermediates, APIs and finished drug preparations.

Fuzhou FUL Fluid Equipment & Pharmaceutical Co., Ltd business radiates to all levels, including direct supply cooperation with government departments and industry representatives, as well as establishing supply cooperation relationship with retail industry. We supply high quality, safe and effective medicines and medical equipment to governments, hospitals, clinics and licensed pharmacies in different countries with timely and effective services at reasonable prices.

At present Fuzhou FUL Fluid Equipment & Pharmaceutical Co., Ltd has the  authorization to sell its intermediates and APIs,and has the authorizations of CSPC & HUABEI PHARM sell its finished drug preparations;then FUL is the only manufacture in China which can supply the complete service from pharmaceutical produciton lines,intermediates and APIs to finished drug preparations and vaccines.Then we are seeking the professional pharmaceutical enterprices to work together for further cooperations.




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