Item nanme:cimetidine Tablets Item character:This product is light green cystic film coated tablets.
Indication:
It is used to treat duodenal ulcer, gastric ulcer, reflux esophagitis, stress ulcer and Zollinger Ellison syndrome
Item specifications:0.2g*100s/box
Usage and dosage:This medicine should be used according to the doctor's prescription. adult:
(1) For the treatment of duodenal ulcer or pathological hypersecretion, take 0.2g ~ 0.4g once, 2-4 times a day, after meal and before going to bed, or 0.8g once, before going to bed.
(2) To prevent ulcer recurrence, take 0.4g at a time before going to bed;
(3) The dosage for patients with renal insufficiency was reduced to 0.2g once every 12 hours.
(4) The dosage of elderly patients decreased.
Adverse reactions Generally speaking, adverse reactions of this product are not common, and usually disappear after continued medication or withdrawal.
1. The more common adverse reactions are diarrhea, fatigue, dizziness, drowsiness, headache and rash.
2. This product has mild anti androgen effect. When the dosage is large (more than 1.6g per day), it can cause male breast development, female milk overflow, decreased sexual desire, impotence, decreased sperm count, etc. and disappear after stopping the drug.
3. This product can pass through the blood cerebrospinal fluid barrier and has certain neurotoxicity. Mental disorders are occasionally seen. Anxiety, depression, anxiety, delirium, hallucination and disorientation are common in elderly and seriously ill patients. Generally, the symptoms disappear 3-4 days after drug withdrawal. In the treatment of gastrointestinal complications of alcoholics, tremor delirium can appear, which is similar to abstinence syndrome;
4. * rare adverse reactions include allergic reaction, fever, arthralgia, myalgia, interstitial nephritis, urinary retention, liver toxicity, and pancreatitis.
5. Very few people have leukopenia and agranulocytosis. These people suffer from other serious diseases and receive drugs and treatments known to reduce blood cells. Thrombocytopenia and aplastic anemia are rarely reported. Occasionally, plasma creatinine or serum transaminase increased. Very rare hepatitis.
6. Bradycardia, tachycardia and heart block, as well as allergic vasculitis are rarely reported with H2 receptor blockers. All these reactions usually disappear after drug withdrawal.
Taboo:
It is forbidden for those who are allergic to this product.
Matters needing attention:
1. Patients with cancerous ulcer should be clearly diagnosed before use to avoid delaying treatment.
2. Due to the decline of renal function, the clearance of this product decreases and slows down in elderly patients, which can lead to the increase of blood drug concentration, so they are more prone to toxic reactions, dizziness, delirium and other symptoms.
3. Please follow the doctor's advice if you have a history of drug allergy.
4. Interference of diagnosis: false positive results can appear in gastric occult blood test within 15 minutes after oral administration; The concentration of blood salicylic acid, serum creatinine, prolactin and aminotransferase may increase; Parathyroid hormone concentration may decrease.
5. In order to avoid nephrotoxicity, renal function should be checked during medication.
6. This product has a certain inhibitory effect on bone marrow. Pay attention to check the hemogram during medication.
7. The neurotoxic symptoms of this product are very similar to those caused by central anticholinergic drugs. It can be treated with cholinergic drug physostigmine to improve the symptoms. Therefore, it should be avoided to use this product together with central anticholinergic drugs to prevent aggravating central neurotoxicity.
8. in elderly patients, chronic lung disease, diabetes and immunodeficiency patients, the risk of community acquired pneumonia with H2- receptor antagonists may increase. A large epidemiological study showed an increased risk performance of community-acquired pneumonia compared with patients receiving H2 receptor antagonists.
9. The following situations should be used with caution:
(1) Severe heart and respiratory diseases.
(2) In patients with systemic lupus erythematosus (SLE), the bone marrow toxicity of cimetidine may be increased.
(3) Organic encephalopathy.
(4) Liver and kidney function damage.
10. Please keep this medicine out of the reach of children.n.
Medication for pregnant and lactating women:
This product can pass through the placental barrier and enter milk. It is forbidden for pregnant and lactating women.
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Our Manufacture Factory Fuzhou FUL Fluid Equipment & Pharmaceutical Co., Ltd is a comprehensive enterprise which integrates R & D, production and construction of pharmaceutical production equipments, development and transfer of biotechnology, and cooperative production and sales of drugs and vaccines. The self-developed pharmaceutical production equipment branded FUL has been put into operation in many well-known pharmaceutical enterprises, CSPC and also cooperates with many well-known pharmaceutical enterprises in production and sales, including pharmaceutical intermediates, APIs and finished drug preparations.
Fuzhou FUL Fluid Equipment & Pharmaceutical Co., Ltd business radiates to all levels, including direct supply cooperation with government departments and industry representatives, as well as establishing supply cooperation relationship with retail industry. We supply high quality, safe and effective medicines and medical equipment to governments, hospitals, clinics and licensed pharmacies in different countries with timely and effective services at reasonable prices.
At present Fuzhou FUL Fluid Equipment & Pharmaceutical Co., Ltd has the authorization to sell its intermediates and APIs,and has the authorizations of CSPC & HUABEI PHARM sell its finished drug preparations;then FUL is the only manufacture in China which can supply the complete service from pharmaceutical produciton lines,intermediates and APIs to finished drug preparations and vaccines.Then we are seeking the professional pharmaceutical enterprices to work together for further cooperations.