Griseofulvin Tablets for The Treatment of Tinea Cruris, Tinea Pedis and Tinea Onychylosis, Ringworm Rhizoma Crimson, Ringworm Rhizoma

• Customization: Available
• Name: Ringworm Rhizoma
• Transport Package: Carton
• Model NO.: CF036-1
• Trademark: FUL
• Origin: China
• Production Capacity: 100000/Month

Product Description

Griseofulvin tablets

Generic name griseofulvin tablet

Main ingredients The main ingredient of this product is griseofulvin.

Indications This product is suitable for the treatment of a variety of tinea capitis, tinea pedicle, tinea body, tinea cruris, tinea pedis and tinea onychylosis. The above mentioned psoriasis is caused by ringworm rhizoma crimson, ringworm rhizoma, ringworm rhizoma, ringworm interphalangeal rhizoma, as well as microsporidia auduin, microsporidia Canis, microsporidia gypsum and flocculent epidermis. This product should not be used for mild, limited superficial fungal infection and local use of antifungal drugs have been effective. Griseofulfomycin was not effective against Candida, Histoplasma, Actinomycetes, Sporotrichum, Blastomycetes, Coccidia, Nucardia, Cryptococcus and other infections as well as tinea tinea.

Adverse Reactions 1. Nervous system headache is common and can occur in about 10% of patients. It is more serious at the beginning and can be alleviated by continuing medication. Others have somnolence, fatigue, etc. Occasionally vertigo, ataxia and peripheral neuritis occur.

2. Digestive system A few patients may have upper abdominal discomfort, nausea or diarrhea, which is generally mild and tolerated by patients.

3. Anaphylaxis can occur in about 3% of patients with skin rash, occasionally angioneurotic edema, persistent urticaria, exfoliative dermatitis, and a few patients with photosensitive dermatitis.

4. This product can cause peripheral blood leukocyte decrease, can cause hepatic toxicity and proteinuria occasionally.

Contraindicated porphyria, liver failure, pregnant women and people allergic to this product are contraindicated.

Note 1. Since griseofulvin was obtained from penicillium, it is speculated that this drug may be cross-allergic to penicillins or penicillamine. However, this situation has not been clinically confirmed, but patients with penicillin allergy still need to be cautious when using this product and observe closely.

2. Griseofulvin has been shown to be tumorigenic in animal experiments.

3. This product may occasionally cause hepatotoxicity, people with existing liver disease or liver function damage should decide whether to use it after weighing the advantages and disadvantages.

4. This product can induce porphyria, lupus erythematosus, lupus patients with lupus erythematosus if there are indications of the application of this drug must weigh the advantages and disadvantages after the decision.

5. Periphereal hemogram, liver function, blood urea nitrogen, creatinine and urine routine should be checked regularly during treatment.

6. This article can be taken together at meal or after meal, with high fat meal is the best, because it can reduce the reaction of gastrointestinal tract and increase drug absorption.

7. To prevent recurrence, treatment should continue until clinical symptoms are resolved and laboratory tests confirm that the pathogen has been completely eradicated. The general course of treatment is: tinea capitis 8 ~ 10 weeks; 2 ~ 4 weeks of ringworm; Tinea pedis 4 to 8 weeks; At least 4 months of onychylosis digitata; Onychylosis toenia for at least 6 months; But the recurrence rate of onychomycosis toe is still high.

8. Usually need to give appropriate local drug use at the same time, this is particularly important to tinea pedis.

9. Male patients should use contraception during treatment and for at least six months after treatment.

Pregnant women and lactating women have been proved to have teratogenic effects by animal experiments, so pregnant women should not use this product. Women of childbearing age were given contraceptive measures during treatment and continued until one month after the end of treatment.

Data on the use of this product in children under 2 years of age are lacking.

There is no research data on the application of this product and its relationship with age in the elderly.

1. When taken together with ethanol, tachycardia, sweating, flushing of the skin, etc., should not be used together.

2. When used together with warfarin, coumarin and other anticoagulants, this product may make the liver of the first two drugs replace the strength of anticoagulants and weaken the effect of anticoagulants, so it is necessary to monitor the prothrombin time to adjust the dose.

3. When combined with primoridone and phenobarbital drugs, the antifungal effect of this product can be weakened, which may be related to the reduced absorption of this product by barbiturates, and the decrease of blood drug concentration due to the induction of liver enzymes to inactivate and increase the speed of this product, so the combination of this kind of drugs and this product should be avoided.

4. The combination of estrogen contraceptives and this product can reduce the effect of oral contraceptives, which may be related to the decrease of blood drug concentration caused by this product's strengthening of the metabolism of this type of drugs in the liver, so the combination of the two should be avoided.

Drug overdose is mainly taken symptomatic therapy and supportive therapy, such as gastric lavage, emetic and fluid rehydration.

Toxicology of the drug This product is mainly on the tinea trichoderma, microspore bacteria, epidermal tinea fungus and other shallow fungi have a good antibacterial effect. It has no antibacterial effect on Candida, Cryptococcus, Histoplasma, Sporotrichum, Blastomycetes and Coccidiococcus. It inhibits fungal growth by interfering with the synthesis of nucleic acid.

Pharmacokinetics The oral absorption of this product varies with different preparations. The drug can be absorbed by 25% ~ 70% in the microgranular form, and almost all in the ultramicrogranular form after oral administration. Eating fat can significantly increase the degree of absorption. The serum protein binding rate of this product is about 80%. After absorption, this product can be deposited in the skin, hair and nail cuticle, and its keratin combined to prevent the continued invasion of sensitive skin tinea fungus, pathogenic fungi existing in the superficial cuticle with the loss of skin or hair and leave the human body, only a small amount of distribution to other body fluids and tissues. It can also enter fetal circulation and be secreted from breast milk. The main metabolites of this product are 6-methylgriseofulvin and its gluconaldoxide. The blood elimination half-life (t1/2β) is 14 ~ 24 hours. Less than 1% of the product is excreted from urine in its original form, and about 16% ~ 36% are excreted from feces in its original form.

Storage Storage sealed storage.


FAQ
1.who are we?
We are based in Fujian, China, start from 2000,sell to North America(40.00%),Southeast Asia(25.00%),Western Europe(25.00%),Africa(10.00%).There are total about 50 people in our office.

2. how can we guarantee quality?
Always a pre-production sample before mass production;
Always final Inspection before shipment;

3.what can you buy from us?
Pharmaceutical production lines,Intermediates,APIs,Finished Drug Preparations & Vaccines.

4. why should you buy from us not from other suppliers?
We have our own manufacture factories and one professional sales team working for the clients all over the world.

5. what services can we provide?
Accepted Delivery Terms: FOB,CIF,EXW,DDP,Express Delivery;
Accepted Payment Currency:USD,EUR,CAD,AUD,GBP,CNY;
Accepted Payment Type: T/T,L/C,PayPal,Western Union;
Language Spoken:English,Chinese,Japanese

Our Ddvantage:
1. Quick delivery
2. Online payment
3. Quality assurance
4. Welcome big order
5. After-sales service 24 hours
6. Competitive advantage products
7. Our value information is "Quality is our culture"
8. Work with us to provide you with secure funds, your business is securely protected, our advantages

Our Service
a)  Free amples can be provided.
b) Guide customers through professional technology and teach them how to use our products after sale
c) Determine the lowest price of high-quality products
1. Skilled experience: Our company is a leading manufacturer of professional production in China pharmaceutical field for many years.
2. The highest quality: to ensure high quality, once any problems are found, the package will be re-shipped for you.
3. Safe transportation: by air express (FedEx, UPS, DHL, EMS). It is recommended that you choose the most professional freight forwarder.
4. Fast delivery: We have stock, so once payment is received, we can deliver quickly.
5. Quality service: We will provide you with enthusiastic after-sales service. If you have any questions, we will reply to youwithin 24 hours.
6. Competitive price: discounts will be obtained when making large orders.

Our Manufacture Factory
Fuzhou FUL Fluid Equipment & Pharmaceutical Co., Ltd is a comprehensive enterprise which integrates R & D, production and construction of pharmaceutical production equipments, development and transfer of biotechnology, and cooperative production and sales of drugs and vaccines. The self-developed pharmaceutical production equipment branded FUL has been put into operation in many well-known pharmaceutical enterprises such as SINOPHARM, CSPC and also cooperates with many well-known pharmaceutical enterprises in production and sales, including pharmaceutical intermediates, APIs and finished drug preparations.

Fuzhou FUL Fluid Equipment & Pharmaceutical Co., Ltd business radiates to all levels, including direct supply cooperation with government departments and industry representatives, as well as establishing supply cooperation relationship with retail industry. We supply high quality, safe and effective medicines and medical equipment to governments, hospitals, clinics and licensed pharmacies in different countries with timely and effective services at reasonable prices.

At present Fuzhou FUL Fluid Equipment & Pharmaceutical Co., Ltd has the SINOPHARM authorization to sell its intermediates and APIs,and has the authorizations of CSPC & HUABEI PHARM sell its finished drug preparations;then FUL is the only manufacture in China which can supply the complete service from pharmaceutical produciton lines,intermediates and APIs to finished drug preparations and vaccines.Then we are seeking the professional pharmaceutical enterprices to work together for further cooperations.

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