Item nanme: Digoxin tablets Item character:The goods is white
Indication: 1. For acute and chronic cardiac insufficiency such as hypertension, valvular heart disease, congenital heart disease, etc.It is particularly suitable for atrial insufficiency with rapid ventricular rate atrial fibrillation.It is less effective for pulmonary heart disease, severe myocardial ischemia, active myocarditis and cardiac insufficiency due to extracardiac factors such as severe anemia, hypothyroidism and vitamin B1 deficiency.
2. Used to control ventricular rate and supraventricular tachycardia in patients with atrial fibrillation and flutter with rapid ventricular rate.
Item specifications:0.25mg*30tab/box
Usage and dosage:Adult dosage, oral:
Commonly used 0.125-0.5mg (0.5-2 tablets), once a day, 7 days to reach steady-state blood drug concentration;If a fast loading dose is reached, 0.25 mg (1 tablet) can be administered every 6-8 hours with a total dose of 0.75-1.25 mg/day (3-5 tablets per day). Maintenance dose is 0.125-0.5 mg once a day (0.5-2 tablets per day).
Common dosage for children, oral:
The total amount of this product is 0.02~0.03mg/kg for premature infants.Neonates under one month old, 0.03-0.04mg/kg: 1-2 years old, 0.05-0.06mg/kg;2-5 years old, 0.03-0.04mg/kg;5-10 years old, 0.02-0.035mg/kg;For adults aged 10 years or over, give the total amount of the product 3 times or every 6-8 hours as usual.Maintenance ranges from 1/5 to 1/3 of the total amount, divided twice, once every 12 hours or once a day.Careful titration of doses and close monitoring of blood drug concentrations and electrocardiograms are required in infants, especially premature infants.Recent studies have shown that digoxin, given a certain dose daily, can achieve a stable concentration in vivo and play a full effect after 6-7 days. Therefore, the patients who are in a less urgent condition and are prone to poisoning can be treated by 5.5 daily.μG/kg can also achieve satisfactory therapeutic effect and reduce the incidence of poisoning.
Adverse reactions 1. Common adverse reactions include arrhythmic effects, poor gastric intake or nausea, vomiting (stimulating the medullary center), lower abdominal pain, abnormal weakness, and weakness.
2. Rare reactions include blurred vision or "color vision", such as yellow vision, green vision, diarrhea, and central nervous system reactions such as depression or confusion.
3. Rare reactions include lethargy, headache and rash, measles-seeking (allergic reactions).
4. Among the manifestations of digitalis poisoning, arrhythmias are the most important. Ventricular premature beats are the most common, accounting for about 33% of adverse reactions to arrhythmias.Secondly, atrioventricular block, paroxysmal or accelerated junctional tachycardia, paroxysmal atrial tachycardia with atrioventricular block, ventricular tachycardia, sinus arrest, ventricular fibrillation, etc.Cardiac arrhythmias are more common in children than in other reactions, but ventricular arrhythmias are less common in adults.Newborns may have prolonged P-R intervals.
Taboo: In combination with calcium injection;Poisoning by any digitalis preparation;Ventricular tachycardia and ventricular fibrillation;Obstructive hypertrophic cardiomyopathy (with systolic dysfunction or atrial fibrillation may still be considered);Preexcitation syndrome with atrial fibrillation or flutter.
Matters needing attention: 1. It should not be compatible with acids and bases.
2. Use cautiously: hypokalemia;Incomplete atrioventricular block;Hypercalcemia;Hypothyroidism;Ischemic heart disease;Miocardial infarction;Myocarditis;Renal function impairment.
3. Follow-up examination should be paid attention to during medication: blood pressure, heart rate and heart rhythm;ECG;Cardiac function monitoring;Electrolytes, especially potassium, calcium and magnesium;Renal function;Blood concentration of digoxin should be determined when digitalis poisoning is suspected.In excess, the toxic manifestations usually subside 1 to 2 days after withdrawal due to small accumulation.
4. Pay attention to monitoring the blood concentration of digoxin when using it.
5. The dosage of this product should be individualized.
Medication for pregnant and lactating women: This product can pass through the placenta, so maternal dosage may increase in the third trimester of pregnancy and should be reduced 6 weeks after delivery.This product can be discharged into breast milk and should be used in breast-feeding women with trade-offs between advantages and disadvantages
FAQ 1.who are we? We are based in Fujian, China, start from 2000,sell to North America(40.00%),Southeast Asia(25.00%),Western Europe(25.00%),Africa(10.00%).There are total about 50 people in our office.
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Our Service a) Free amples can be provided. b) Guide customers through professional technology and teach them how to use our products after sale c) Determine the lowest price of high-quality products 1. Skilled experience: Our company is a leading manufacturer of professional production in Chinapharmaceutical field for manyyears. 2. The highest quality: to ensure high quality, once any problems are found, the package will be re-shipped for you. 3. Safe transportation: by air express (FedEx, UPS, DHL, EMS). It is recommended that you choose the most professional freightforwarder. 4. Fast delivery: We have stock, so once payment is received, we can deliver quickly. 5. Quality service: We will provide you with enthusiastic after-sales service. If you have any questions, we will reply to youwithin 24 hours. 6. Competitive price: discounts will be obtained when making large orders.
Our Manufacture Factory Fuzhou FUL Fluid Equipment & Pharmaceutical Co., Ltd is a comprehensive enterprise which integrates R & D, production and construction of pharmaceutical production equipments, development and transfer of biotechnology, and cooperative production and sales of drugs and vaccines. The self-developed pharmaceutical production equipment branded FUL has been put into operation in many well-known pharmaceutical enterprises , CSPC and also cooperates with many well-known pharmaceutical enterprises in production and sales, including pharmaceutical intermediates, APIs and finished drug preparations.
Fuzhou FUL Fluid Equipment & Pharmaceutical Co., Ltd business radiates to all levels, including direct supply cooperation with government departments and industry representatives, as well as establishing supply cooperation relationship with retail industry. We supply high quality, safe and effective medicines and medical equipment to governments, hospitals, clinics and licensed pharmacies in different countries with timely and effective services at reasonable prices.
At present Fuzhou FUL Fluid Equipment & Pharmaceutical Co., Ltd has the authorization to sell its intermediates and APIs,and has the authorizations of CSPC & HUABEI PHARM sell its finished drug preparations;then FUL is the only manufacture in China which can supply the complete service from pharmaceutical produciton lines,intermediates and APIs to finished drug preparations and vaccines.Then we are seeking the professional pharmaceutical enterprices to work together for further cooperations.
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